Repeatability of two semi-automatic artificial intelligence approaches for tumor segmentation in PET

نویسندگان

چکیده

Abstract Background Positron emission tomography (PET) is routinely used for cancer staging and treatment follow-up. Metabolic active tumor volume (MATV) as well total MATV (TMATV—including primary tumor, lymph nodes metastasis) and/or lesion glycolysis derived from PET images have been identified prognostic factor or the evaluation of efficacy in patients. To this end, a segmentation approach with high precision repeatability important. However, implementation repeatable accurate algorithm remains an ongoing challenge. Methods In study, we compare two semi-automatic artificial intelligence (AI)-based methods conventional approaches terms repeatability. One based on textural feature (TF) designed tumors metastasis. Moreover, convolutional neural network (CNN) trained. The algorithms are trained, validated tested using lung dataset. accuracy both compared Jaccard coefficient (JC). Additionally, externally fully independent test–retest those majority vote (MV2, MV3) approaches, 41%SUV MAX , SUV > 4 (SUV4). Repeatability assessed coefficients (TRT%) intraclass correlation (ICC). An ICC 0.9 was regarded representing excellent Results segmentations reference good (JC median TF: 0.7, CNN: 0.73). Both outperformed most other (TRT% mean: 13.0%, 13.9%, MV2: 14.1%, MV3: 28.1%, : SUV4: 18.1%) (TF: 0.98, 0.97, 0.99, 0.73, 0.81, 0.68). Conclusion AI-based study provided better than approaches. lead to metastasis therefore candidates segmentation.

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ژورنال

عنوان ژورنال: EJNMMI research

سال: 2021

ISSN: ['2191-219X']

DOI: https://doi.org/10.1186/s13550-020-00744-9